|
Symbol Name ID |
Lep
leptin MGI:104663 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Orthostatic hypotension due to autonomic dysfunction |
| Disease(s) Associated with LEP | |
| congenital leptin deficiency |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal arteriole morphology |
abnormal retina vasculature morphology |
retina neovascularization |
abnormal myocardial fiber morphology |
increased myocardial fiber size |
heart left ventricle hypertrophy |
decreased heart weight |
increased heart weight |
abnormal cardiovascular system physiology |
increased cardiac stroke volume |
decreased cardiac muscle contractility |
decreased heart rate |
prolonged QRS complex duration |
abnormal myocardial fiber physiology |
abnormal response to cardiac infarction |
hypotension |
abnormal vascular wound healing |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Lepm1Yst/Lepm1Yst | |||||||||||||||||||
| Lepob/Lepob | * | ||||||||||||||||||
| Leptm1b(EUCOMM)Hmgu/Leptm1b(EUCOMM)Hmgu | |||||||||||||||||||
| Tg(Apcs-Lep)1Yog/? | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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